Steroids Broke Her Bones Before She Became the Queen of Biohacking | Dr. Lauren Leiva
As a teenager, Lauren Leiva was diagnosed with Crohn's disease. The steroids doctors put her on broke her bones, changed the shape of her face, and left her looking sick. She was in and out of hospitals for years, treated by a system that was guessing as much as it was healing, and she remembers feeling like an experiment rather than a patient. That experience is the reason she built her entire practice around one idea: do no harm. Now known as "The Queen of Biohacking," Dr. Leiva works with…
Can Ketosis Be the Answer to Easy Weight Loss | Ben Azadi
Health has been a sensitive topic in the United States for nearly half a century at this point. So the fact that 9 out of 10 Americans are not metabolically healthy is alarming, to say the least. While most people are unaware of this, those who are often try to fix the problem by changing their diet. Sure, that helps, but it usually misses the actual switch that needs to be flipped. And that switch is, of course, insulin. Ben Azadi, a returning guest, has spent years teaching people how to work with…
Optimism Cuts Your Risk of Heart Death by 35% | Dr. Alan Rozanski
Cigarette smoking rates have dropped to historic lows. High-quality generic statins are highly affordable. With all of the advanced diagnostics, effective medications, and a better overall understanding of cardiovascular risk, managing cholesterol is easier than ever. Yet, heart disease still causes roughly 1 in every 3 deaths in the US and is, in fact, the number one cause of death worldwide. For decades, Dr. Alan Rozanski kept seeing patients whose hearts were failing them in ways cholesterol…
Your Gut Bacteria Could Predict Parkinson's a Decade Early | Shaina Cahill
Nearly 12 million people are living with Parkinson's disease worldwide, and it's the fastest-growing neurological disorder on the planet. By 2050, that number is expected to more than double to 25 million cases. Researchers are still racing to understand what actually triggers the disease long before a diagnosis ever happens. Shaina Cahill thinks the answer might start somewhere nobody's looking, and that's the gut. Years before a Parkinson's diagnosis, most patients already show the same GI…
The Ancient Survival Switch Nobody Told You Was Still Running | Chris Mearns
About 75% of people are actively trying to cut down on or completely cut out sugar from their diet. That is not surprising, because sugar contributes to serious illnesses such as type 2 diabetes, heart disease, and even cancer. Unfortunately, cutting out every gram of added sugar might not be enough. Even if you manage to avoid sugar completely, your body will still produce fructose from stress, dehydration, alcohol, and high glycemic carbs. That is what Chris Mearns has spent years studying. Chris…
How to Avoid Breaking a Hip as You Grow Older | Dr. John Neustadt
A bone fracture happens roughly every 30 seconds. However, most people do not find out their bones are fragile until they are already on the floor. By then, the window to prevent it has usually been open for decades. For women, the lifetime risk of breaking a bone equals the combined risk of breast, uterine, and ovarian cancer. The bone density test most doctors rely on to catch this predicts less than half the people who will fracture. For men, it is even worse: closer to one in five Dr. John…
How a Keto Diet Can Potentially Help People Get Off Psychiatric Medications | Matthew Bernstein, MD
Dr. Bernstein is a clinical psychiatrist with 25 years of experience. But when two of his three sons developed autoimmune encephalitis, the conventional medicine he had trusted his entire career had almost nothing to offer. So he went out and found the answers himself. What Dr. Bernstein found made me so interested in sitting down and having a discussion with him. He believes depression, anxiety, and bipolar disorder are not brain chemistry problems. Instead, he thinks these are metabolic disorders, and…
What Can We Learn From the Most Genetically Modified Human Alive? | Liz Parrish
In 2015, Liz Parrish flew to Colombia and let someone inject an untested gene therapy into her body 150 times. She texted her kids that she loved them before it started. When it was over, she went for nachos. Ten years later, her telomeres are longer than when she started, and she has taken 12 gene therapies in total. Her decade of self-experimentation has produced peer-reviewed data, a growing protocol of gene therapies, and a company training its sights on making biological aging optional. Our…
You Can Fight Prostate Cancer Without Losing What Makes You a Man With Dr. Stephen Petteruti
Roughly 1 in 8 men will be diagnosed with prostate cancer in their lifetime. Most will get a high PSA, go to a urologist, get a biopsy, and end up in surgery or radiation. A 15-year government-funded study published in the New England Journal of Medicine found that none of it changed the death rate. Bringing that research to the table is Dr. Stephen Petteruti, a men's health physician with over 30 years in practice. He thinks there is a better way to handle prostate cancer that can keep men out of the…
Your Glasses Are Making Your Eyes Lazier and Vision Worse With Dr. Bryce Appelbaum
Every year, your prescription gets stronger. Every year, your optometrist hands you a new lens and sends you home. Nobody ever asks why it keeps changing. That's the question Dr. Bryce Appelbaum has been asking for two decades. The answer has nothing to do with your eyes. Bryce and I get into why your prescription should not keep getting stronger every year, and what it means for your brain when it does. We talk about how he took his work from kids with learning delays all the way to the NBA,…
How 140 Genes Can Tell You Everything About Your Health With Dr. Sam Shay
Most people think genetic testing is too complex, too expensive, or too tied to "you have the cancer gene." Dr. Sam Shay says you only need 140 genes out of your 20,000 to understand what's actually driving your health. After nearly 200 episodes, Dr. Sam Shay is back on the show, picking up where we left off in our first conversation about how your genes shape the way your body handles food, stress, and inflammation. This time, we go deeper into the framework that took him from being chronically…
How an Auditor Rewrote the Science of Gut Health and Brain Disease With Martha Carlin
Martha Carlin wasn't a scientist. She was an auditor at one of the largest accounting firms in the world. Then her husband was diagnosed with Parkinson's at 44. She couldn't just sit back and watch him succumb to it. So she set out to find what caused it. What followed was a 20-year-long second career. Within a month of throwing out the pantry and filtering the family's water, her husband's tremor was already retreating. He managed to stay off medication for years. When she stumbled onto a book…